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Exelixis and Sankyo link up

March 27, 2006 | A version of this story appeared in Volume 84, Issue 13

Exelixis and Sankyo have agreed to collaborate on the discovery, development, and commercialization of small-molecule compounds targeting the mineralocorticoid receptor (MR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic diseases. Exelixis, which has developed a series of MR antagonists, will receive $20 million in up-front payments as well as unspecified research funding, milestone payments, and royalties.

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