Issue Date: May 29, 2006
Free radicals and neural diseases
A new study offers the first evidence that explains the link between cellular stress caused by free radicals and the protein misfolding that is associated with several neurodegenerative diseases, according to its authors. Patients with these diseases, which include Parkinson's and Alzheimer's, produce excess amounts of nitric oxide free radical. Stuart A. Lipton of Burnham Institute for Medical Research in La Jolla, Calif., and colleagues report that the NO group S-nitrosylates critical cysteine . . .
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