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Web Date: September 19, 2006

Pfizer Licenses TransTech Compounds

Deal involves small and large molecules for treatment of Alzheimer's
Department: Business

Pfizer has signed a licensing agreement with TransTech Pharma for the development and commercialization of small- and large-molecule compounds under development by TransTech for the treatment of Alzheimer's disease and other diseases.

The compounds target the receptor for advanced glycation end products (RAGE). The most advanced of the compounds are TTP488, an orally available small-molecule candidate that has completed Phase II clinical trials in patients with Alzheimer???s disease and diabetic nephropathy, and TTP4000, . . .

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