Issue Date: March 19, 2007
DNA methylation may help form memories
Once cells in an embryo have differentiated sufficiently, DNA methyltransferase (DNMT) attaches methyl groups to select regions of DNA to permanently switch off targeted genes. Researchers at the University of Alabama, Birmingham, propose that brain cells have adapted this technique as a means to store memories (Neuron 2007, 53, 857). Neurobiologists Courtney A. Miller and J. David Sweatt began a study by conditioning rats with a series of mild shocks in a training chamber. . . .
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