Volume 85 Issue 12 | p. 45 | Concentrates
Issue Date: March 19, 2007

DNA methylation may help form memories

Department: Science & Technology

Once cells in an embryo have differentiated sufficiently, DNA methyltransferase (DNMT) attaches methyl groups to select regions of DNA to permanently switch off targeted genes. Researchers at the University of Alabama, Birmingham, propose that brain cells have adapted this technique as a means to store memories (Neuron 2007, 53, 857). Neurobiologists Courtney A. Miller and J. David Sweatt began a study by conditioning rats with a series of mild shocks in a training chamber. . . .

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