Thin Is In | Chemical & Engineering News
Volume 85 Issue 14 | p. 56 | Concentrates
Issue Date: April 2, 2007

Thin Is In

Department: Science & Technology

Long, skinny micelles last longer in the blood than their spherical counterparts. Dennis E. Discher and coworkers at the University of Pennsylvania compare thin cylindrical micelles called filomicelles (shown) with spherical nanoparticles with similar surface chemistry (Nat. Nanotechnol., DOI: 10.1038/nnano.2007.70). The filomicelles are made of polyethylene glycol (PEG) mixed with either polyethylethylene or biodegradable polycapralactone. When injected in rats, the filomicelles circulate in the blood 10 times longer than similar spherical particles with PEG on . . .

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