Issue Date: April 2, 2007
Thin Is In
Long, skinny micelles last longer in the blood than their spherical counterparts. Dennis E. Discher and coworkers at the University of Pennsylvania compare thin cylindrical micelles called filomicelles (shown) with spherical nanoparticles with similar surface chemistry (Nat. Nanotechnol., DOI: 10.1038/nnano.2007.70). The filomicelles are made of polyethylene glycol (PEG) mixed with either polyethylethylene or biodegradable polycapralactone. When injected in rats, the filomicelles circulate in the blood 10 times longer than similar spherical particles with PEG on . . .
To view the rest of this content, please log in with your ACS ID.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society