Steric Zippers Play Key Role In Amyloid Fibrils | Chemical & Engineering News
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Web Date: May 3, 2007

Steric Zippers Play Key Role In Amyloid Fibrils

Study indicates that Alzheimer's, type 2 diabetes, and other degenerative diseases are closely related at the molecular level
Department: Science & Technology

Two years ago, David Eisenberg of the University of California, Los Angeles, and a collaborative international group obtained the first atomic structure of an amyloid fibril formed from a yeast prion protein and found that an interdigitated β-sheet structure called a steric zipper was essential to fibril formation (C&EN, June 13, 2005, page 9).

Now, the same . . .

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