Structure of Ebola Virus Surface Glycoprotein | Chemical & Engineering News
Volume 86 Issue 28 | p. 34 | Concentrates
Issue Date: July 14, 2008

Structure of Ebola Virus Surface Glycoprotein

Department: Science & Technology
News Channels: JACS In C&EN

After a five-year effort, researchers have determined the structure of the Ebola virus surface glycoprotein, which enables the virus to enter cells. They analyzed the glycoprotein bound to an antibody from a rare survivor of a 1995 Ebola outbreak in Congo (Nature 2008, 454, 177). The work aids in understanding the mechanism by which Ebola virus enters cells and could help lead to immunotherapeutics. Ebola virus kills more than half of those infected by causing . . .

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