Volume 86 Issue 37 | pp. 38-40
Issue Date: September 15, 2008
Advances could spur treatments for more symptoms than current drugs address
Pfizer's drug candidate for schizophrenia (stick model) blocks a specific phosphodiesterase enzyme. Protein surfaces contacting the drug are shown in a space-filling format. Amino acids and a water molecule that make contact with the drug are shown in ball-and-stick form.
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