Issue Date: November 10, 2008
Bacteria Trigger Blood Coagulation
Bacterial infections in blood are often accompanied by blood coagulation, but this phenomenon has been believed to result from immune and inflammatory responses. Rustem F. Ismagilov of the University of Chicago and coworkers now show that the bacteria themselves can trigger coagulation under the right circumstances (Nat. Chem. Biol., DOI: 10.1038/nchembio.124). The researchers found that activation of blood coagulation depends on the clustering of bacterial cells rather than on the total amount of bacteria . . .
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