Issue Date: March 9, 2009
CEM Launches Two Microwave Instruments
CEM Corp. has introduced a new microwave synthesizer and a new peptide cleavage system. The Explorer-12 Hybrid is the smallest automated microwave synthesizer commercially available, the company says. It can run both open-vessel reflux and pressurized reactions. The sample deck holds up to 12 10-mL or six 35-mL pressurized vials. The company’s new Accent Cleavage System can perform a full peptide cleavage in less than 30 minutes . . .
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Companies Unveil Plans For Faster, Cheaper DNA Sequencing
At last month’s Advances in Genome Biology & Technology meeting in Marco Island, Fla., two genomics companies revealed developments in their technologies that will improve human genome sequencing. San Diego-based Illumina unveiled a “development roadmap,” showing how it plans to generate 25x coverage of a human genome for less than $10,000 by the end of this year. What can now be done in three flow cells will be possible in a single cell, says David Bentley, Illumina’s vice president and chief scientist of DNA sequencing. Such increased efficiency will be achieved by advances in chemistry, hardware, and sequencing algorithms. At the same time, Complete Genomics, based in Mountain View, Calif., released proof-of-concept data for its third-generation human-genome-sequencing technology, which features high-density arrays of DNA nano-balls (clusters of amplified DNA with more than 200 copies of a circular template) and a type of read technology called combinatorial probe-anchor ligation. The company obtained 91x coverage of a Caucasian HapMap sample. Complete Genomics’ technology will be commercially launched in June.
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