Issue Date: March 8, 2010
Predicting Amyloid Formation
Clumps of protein fibrils known as amyloids play a role in a number of diseases, most famously Alzheimer’s and Parkinson’s. These fibrils are rich in β-sheets, a type of flat secondary protein structure. Being able to predict which proteins are likely to form amyloids could provide a way to discover drugs that prevent potential damage.
Scientists have now moved closer to being able to predict what portions of proteins have the ability to form amyloids . . .
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