Issue Date: June 7, 2010
New Molecular Way To Combat The Flu
Hong Kong microbiologists have uncovered a new protein target for treating influenza A, along with a small molecule that prevents viral replication by blocking the protein (Nat. Biotechnol., DOI: 10.1038/nbt.1638). Richard Y. Kao of the University of Hong Kong and coworkers used a forward chemical genetics approach to identify influenza A nucleoprotein as a drug target. The researchers then screened a library of more than 50,000 compounds, taking a closer look . . .
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