Volume 88 Issue 29 | p. 32 | Concentrates
Issue Date: July 19, 2010

CO2 Solvent Could Enhance Stitches

Green solvent infuses biodegradable sutures with an anti-inflammatory drug for sustained-release applications
Department: Science & Technology
Keywords: 2"> supercritical CO2, ketoprofen, sutures, biodegradable

Carbon dioxide, despite its bad reputation as a greenhouse gas, is an inert, nonflammable, recyclable, and inexpensive solvent that is becoming popular for processing pharmaceuticals and biomedical polymers. In one of the latest studies, a team led by Randy D. Weinstein of Villanova University used liquid and supercritical CO2 to infuse biodegradable suture material with the anti-inflammatory drug ketoprofen for sustained-release applications (Ind. Eng. Chem. Res., DOI: . . .

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