Issue Date: September 20, 2010
Monitoring Cellular Metals
Certain transition metals—such as zinc, copper, and iron, three of the most abundant metals in biological systems—are essential to life. Those same metals, however, can also be toxic at excessive concentrations. And although researchers have made progress in identifying individual metal-dependent enzymes and some of the mechanisms involved in essential metal uptake and regulation, there is still a lot to be learned about the location, speciation, and flux of metals within cells. At the American . . .
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