Issue Date: February 8, 2010
Study Strengthens Alzheimer's Link To Cholesterol
Findings on the molecular mechanism of a cholesterol metabolism pathway could aid development of a new class of Alzheimer’s disease therapeutics, according to a research report. Cholesterol metabolism is known to play a role in the accumulation of amyloid β, a peptide associated with Alzheimer’s. Dora M. Kovacs of Harvard Medical School and coworkers previously showed that inhibitors of acyl-coenzyme A:cholesterol acyltransferase (ACAT) reduce amyloid β accumulation in cell and animal tests, but the way . . .
To view the rest of this content, please log in with your ACS ID.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society