Volume 88 Issue 6 | p. 48 | Concentrates
Issue Date: February 8, 2010

Tree Bark Inspires Vaccine Adjuvants

Synthetic saponin analogs have potential to improve immune response to vaccines and thus improve vaccine efficacy
Department: Science & Technology
News Channels: JACS In C&EN
Keywords: vaccines, adjuvants, natural products

Weak antigens used in antitumor and antiviral vaccines often require an adjuvant, a substance that helps stimulate enough of an immune response to make the vaccine effective. But few such adjuvants are currently available. David Y. Gin and colleagues at Memorial Sloan-Kettering Cancer Center, in New York City, are reporting some new compounds that could extend the family of vaccine adjuvants (J. Am. Chem. Soc., DOI: . . .

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