Issue Date: February 15, 2010
Slaying Cancer At Its Roots
James Inglese knew he had to choose carefully. It was 2004, and Inglese, deputy director of the National Institutes of Health’s Chemical Genomics Center (NCGC), had a plan that could save time and resources for scientists screening large chemical libraries for enzyme inhibitors or activators. But he needed just the right protein to test the idea. It had to be something familiar, something well understood, but something that wasn’t such a . . .
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