Slaying Cancer At Its Roots | February 15, 2010 Issue - Vol. 88 Issue 7 | Chemical & Engineering News
Volume 88 Issue 7 | pp. 46-47
Issue Date: February 15, 2010

Slaying Cancer At Its Roots

Revival of classic hypothesis opens auspicious avenues to treatments
Department: Science & Technology
Keywords: Cancer, Inglese, kinase

James Inglese knew he had to choose carefully. It was 2004, and Inglese, deputy director of the National Institutes of Health’s Chemical Genomics Center (NCGC), had a plan that could save time and resources for scientists screening large chemical libraries for enzyme inhibitors or activators. But he needed just the right protein to test the idea. It had to be something familiar, something well understood, but something that wasn’t such a . . .

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