Issue Date: April 18, 2011
Peptide Denies Cell Entry To Ebola Virus
A novel approach to fight Ebola virus uses a designed peptide to inhibit the deadly virus’ entry into host cells. Ebola infection causes a rapidly progressing condition with internal and external bleeding and high fever. The disease has a high mortality rate, and there are currently no approved vaccines or therapies. Infection begins when a viral surface glycoprotein catalyzes fusion between the virus’s membrane and the membrane of endosomes in host cells. C-peptides inhibit similar . . .
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