Issue Date: June 27, 2011
Peptides Block Fibril Formation
Peptides designed to interact with a specific small fraction of an amyloid-forming protein can inhibit fibril formation by the intact protein as well, researchers at the University of California, Los Angeles, recently reported (Nature,DOI: 10.1038/nature10154).
David Eisenberg says his team’s study “validates the strategy” of looking for inhibitors of amyloid fibril formation by concentrating on a small portion of the protein. “At this point, there’s no way of determining atomic-level information for whole . . .
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