Issue Date: July 4, 2011
Rapamycin Diversifies To Fight Early Aging
The immunosuppressant drug rapamycin typically given to organ transplant patients appears to have a new use: treating progeria. Progeria is a rare genetic condition in which young children show signs of aging and die prematurely. There are no proven treatments. The disease is caused by a single-nucleotide gene substitution that leads to production of a mutant protein called progerin, which causes cell senescence. Rapamycin had been shown previously to help prevent aging of cells and . . .
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