Issue Date: July 18, 2011
Cocrystal Engineering Sorts Out Ladderanes
A cocrystallization strategy commonly used in protein chemistry has been redirected to help elucidate the structures of a pair of complex ladderane isomers, possibly the first application of the technique to the structural characterization of small organic molecules (Proc. Natl. Acad. Sci. USA, DOI: 10.1073/pnas.1104352108). Ladderanes are rod-shaped molecules that contain a core set of fused cyclobutane rings. They are used as building blocks in optoelectronics and recently were discovered to be a structural . . .
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