Issue Date: October 3, 2011
Tweezing Apart Amyloids
A clawlike molecule that can unravel the aberrant protein snarls behind diseases such as Alzheimer’s and Parkinson’s may serve as the basis for a new strategy to treat a broad range of protein-misfolding diseases (J. Am. Chem. Soc., DOI: 10.1021/ja206279b).
The protein clumps associated with these diseases are called amyloids. They form when normal proteins in the cell unfold and then . . .
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