Volume 89 Issue 42 | p. 55 | Concentrates
Issue Date: October 17, 2011

Surprise Route To Peptoid Nanosheets

Scientists find that peptoid-based materials form from compressed monolayers
Department: Science & Technology
News Channels: Biological SCENE, JACS In C&EN
Keywords: peptoid, nanosheet, materials science

Nanosheets composed of amphiphilic peptoids (peptide analogs) assemble by an unexpected mechanism that may be applicable to other types of nanosheets. Peptoid nanosheets were first reported last year (C&EN, April 19, 2010, page 7). Their potential applications include sensing, templating, filtering, molecular recognition, and catalysis. Ronald N. Zuckermann and coworkers at Lawrence Berkeley National Laboratory’s Molecular Foundry, who developed the nanosheets, initially believed they form by a nucleation and . . .

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