Volume 89 Issue 43 | pp. 41-43
Issue Date: October 24, 2011

Cancer Stem Cells

Researchers zero in on the pathways that allow cancer to bounce back after treatment
Department: Science & Technology
News Channels: Biological SCENE
Keywords: cancer, medicinal chemistry, oncology, stem cells, differentiation

Take some cells from a tough-to-treat tumor, sort them, and inject each fraction into a different immunodeficient mouse, and only a small percentage of those cells will thrive and form tumors.

This sort of experiment illustrates a concept that has been gaining traction within the cancer research community. Tumors contain a diverse mixture of cells, and only a handful of them can bounce back after treatment. That deadly minority can reproduce indefinitely and differentiate into . . .

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