Issue Date: October 24, 2011
Modifying Messenger RNA
For decades researchers have known that every strand of messenger RNA in a cell has five or six adenosine bases that are methylated, but nobody could figure out why this ubiquitous decoration exists.
Now a team of scientists led by Chuan He at the University of Chicago have found an enzyme that can remove the methyl group from mRNA. This first report that RNA bases can be reversibly modified suggests that RNA . . .
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