Issue Date: November 7, 2011
Catalysis Merger Leads to Mild Arylation
By marrying two catalytic cycles—one mediated by palladium and the other by light—chemists at the University of Michigan have developed a C–H arylation reaction that proceeds at room temperature (J. Am. Chem. Soc., DOI: 10.1021/ja208068w). The merger is “a far-reaching concept” that could extend the capabilities of C–H activation chemistry for making pharmaceuticals and materials, says chemistry professor Melanie S. Sanford, who led the Michigan team.
Aryl-aryl bonds are common . . .
You Do Not Have Access to C&EN Protected Content.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society