Issue Date: November 28, 2011
How A Horseradish Sensor Helps Tylenol Work
Acetaminophen exerts its pain-relieving effects with help from a cation channel protein called TRPA1, according to studies conducted in rodents (Nat. Commun., DOI: 10.1038/ncomms1559). The discovery suggests that TRPA1 could be a viable target for new pain relievers. Also known as paracetamol, acetaminophen is one of the most widely used analgesics. But how it works is still unclear. Among the drug’s proposed targets . . .
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