Issue Date: March 19, 2012
Many diseases, including Alzheimer’s and Parkinson’s, are characterized by the formation of clumps of long protein fibrils. Smaller intermediates that form first are suspected by some scientists to be the actual toxic form of the proteins that help cause these conditions. Stopping such intermediates from forming might thus be preventive or therapeutic, but little has been known about their structures.
Two recent studies provide the first glimpses of what two of those intermediates might look . . .
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