Volume 90 Issue 13 | p. 47 | Concentrates
Issue Date: March 26, 2012

Thermally Stable Nisin Analogs Found

Geobacillins are more stable than nisin at neutral pH and elevated temperatures
Department: Science & Technology
News Channels: Biological SCENE
Keywords: lantibiotics, food preservative, nisin

The lantibiotic nisin has been used for more than 40 years as a food preservative to protect against food-borne pathogens. It has also been approved as a treatment for bovine mastitis. The problem is that nisin isn’t particularly stable at pH 7. Wilfred A. van der Donk and coworkers at the University of Illinois, Urbana-Champaign, have now characterized nisin analogs called geobacillin I and geobacillin II identified in the . . .

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