Issue Date: May 7, 2012
Bespoke Enzymes Push The Envelope
Designed metalloenzymes made by modifying a native protein scaffold have shown unusually high levels of efficiency and longevity and have revealed new details about the way oxidases, the natural enzymes they mimic, may work. The study is an important step in efforts to design customized enzymes for a variety of potential biological and alternative-energy applications.
Most designed enzymes have relatively simple active-site structures, low activity, and limited turnovers (duration of activity). Designing artificial enzymes with . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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