Volume 90 Issue 29 | p. 40 | Concentrates
Issue Date: July 16, 2012

DCAP Antibiotic Takes Aim At Membrane Targets

New broad-spectrum antibiotic goes after slow-growing bacteria
Department: Science & Technology
News Channels: JACS In C&EN, Biological SCENE
Keywords: DCAP, antibiotic, transmembrane potential

Standard antibiotics are usually fine for fighting most fast-growing bacteria, but they typically have trouble treating persistent infections caused by slow-growing dormant and biofilm-associated bacteria. Now, researchers led by Douglas B. Weibel of the University of Wisconsin, Madison, have discovered a broad-spectrum antibiotic capable of killing these types of bacteria (J. Am. Chem. Soc., DOI: 10.1021/ja302542j). The compound, known . . .

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