Volume 90 Issue 29 | p. 41 | Concentrates
Issue Date: July 16, 2012

Sequencing Method Correctly Maps DNA Haplotypes

Sequence variants are determined from the amount of DNA in only 10 to 20 cells
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: DNA sequencing, haplotyping

A new DNA-sequencing method allows researchers to efficiently determine haplotypes—sequence variants that are usually inherited together—using an amount of DNA equivalent to the amount from only 10 to 20 cells. The method was developed by a team led by Brock A. Peters and Radoje Drmanac of Complete Genomics, a Mountain View, Calif., sequencing firm (Nature, DOI: 10.1038/nature11236). The ability to . . .

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