Volume 90 Issue 3 | p. 31 | Concentrates
Issue Date: January 16, 2012

Irradiation Bubbles Improve Virus Imaging

Electron microscopy technique enables scientists to find hidden protein buried in viral capsids, like finding a needle in a haystack
Department: Science & Technology
News Channels: Analytical SCENE, Biological SCENE
Keywords: virus, imaging, bubbles

A moment of laboratory serendipity has led to a bubbly technique that helps scientists image the inner secrets of viruses (Science, DOI: 10.1126/science.1214120). Researchers led by Alasdair C. Steven of the National Institute of Arthritis & Musculoskeletal & Skin Diseases discovered that after an atypically high sequence of electron pulses was delivered to cryogenically frozen samples of viruses in an electron microscope, bubbles of hydrogen-containing gas formed in the . . .

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