Issue Date: February 6, 2012
DNA Nanostructure Controls Transcription
Japanese scientists have designed a DNA nanostructure that mechanically controls gene transcription (J. Am. Chem. Soc., DOI: 10.1021/ja2074856). Hiroshi Sugiyama, Masayuki Endo, and coworkers at Kyoto University attached a tubular DNA nanostructure to a double-stranded DNA template containing a promoter region that is enclosed in the tube. The tube also has single-stranded DNA called toehold strands. When complementary DNA binds . . .
You Do Not Have Access to C&EN Protected Content.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society