Death To Cancer | Chemical & Engineering News
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Web Date: March 26, 2012

Death To Cancer

Drug Development: Researchers harness the natural cell-death pathway to destroy cancer cells and test an experimental drug in an early stage clinical trial
Department: Science & Technology
News Channels: Biological SCENE
Keywords: apoptosis, inhibitor of apoptosis protein, cancer, Smac

Inside each cell is a chemical pathway that, once triggered, marches the cell toward apoptosis--programmed cell death—once the cell is no longer needed. Cancer cells have developed clever ways to subvert apoptosis and continue their malignant growth. Now, researchers have developed an anticancer drug candidate that turns the apoptosis pathway back on in cancer cells, and they have already performed a small study with the . . .

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