Web Date: April 24, 2012
Streamlining Tetrazine Synthesis
Thanks to zinc and nickel catalysts, a newfangled motif for biomolecule labeling might catch on more easily than it could before (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201201117). Thus far, the labels, which feature nitrogen-rich rings called tetrazines, have been relegated to labs with the chemistry chops to work with the multistep and low-yielding syntheses required to make them. The advance might allow more . . .
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