Issue Date: July 29, 2013
Branching Out In Different Ways
An important tool has been missing from the carbohydrate chemist’s toolbox: the ability to easily synthesize libraries of asymmetrically branched N-linked glycans. Without this tool, chemists haven’t been able to use these common molecules—often attached to proteins on cell surfaces—to screen drug candidates and explore ways cells communicate.
Now, a strategy developed by Geert-Jan Boons and coworkers at the Complex Carbohydrate Research Center at the University of Georgia changes that. The work . . .
To view the rest of this content, please log in with your ACS ID.
- Chemical & Engineering News
- ISSN 0009-2347
- Copyright © American Chemical Society