Issue Date: August 5, 2013
New Twist On Chiral Fluorination
Recent advances in organofluorine chemistry have made fluorinated compounds—widely sought as pharmaceuticals and agrochemicals—more readily available than ever before. One of the final frontiers is developing general methods for selectively making compounds with chiral C–F bonds. A European research team has now developed a chiral version of a popular fluorinating reagent that could help streamline such efforts (Angew. Chem. Int. Ed. 2013, DOI: 10.1002/anie.201304845). Véronique . . .
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