Issue Date: September 16, 2013
Key HIV Entry Point Analyzed
For the first time, the structure of the receptor that is the predominant entry point for the AIDS virus to invade human cells has been determined. Knowing the form of the receptor, called CCR5, raises hopes for the discovery of drugs that can block human immunodeficiency virus more effectively than can the drug maraviroc.
When HIV infects someone, it first interacts with CD4 receptors on immune-cell surfaces. This interaction opens the door for a secondary . . .
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