Volume 91 Issue 8 | pp. 32-33
Issue Date: February 25, 2013

Fluorine Chemistry Continues Apace

Researchers stay on a hot streak creating simpler and more efficient reactions for making drugs and pesticides
Department: Science & Technology | Collection: Green Chemistry
News Channels: Organic SCENE, JACS In C&EN
Keywords: fluorine, organometallics, cross-coupling, drug discovery, research trends

Fluorine chemists have been on a roll lately, generating a torrent of research papers reporting new tricks for incorporating fluorine into organic molecules. The field’s abundance of riches has come about in response to a call by pharmaceutical and agrochemical companies to generate new leads for drugs and pesticides.

The interest in fluorine stems from the ability of the small, highly electronegative element to increase the metabolic stability of molecules. It also improves their ability . . .

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