Web Date: December 11, 2013
Unlocked Nucleic Acids Help Silence Genes Selectively
Some biologists have long hoped that small pieces of RNA that silence genes could help wipe out genetic diseases. But developing nucleic acid medications with good drug properties, such as selectivity, has proven difficult. Researchers have now added a new, improved weapon to the silencing arsenal: RNAs containing flexible synthetic nucleic acids. These RNAs selectively and potently inhibit the expression of the mutant genes associated with Huntington’s disease . . .
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- Chemical & Engineering News
- ISSN 0009-2347
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