Issue Date: March 31, 2014
A Practical Path To Morphine Alkaloids
Morphine is an indispensable narcotic drug derived from the opium poppy that has been used for centuries to relieve intense pain. The compound also serves as a precursor to a stable of other useful narcotics, such as codeine and hydromorphone. But chemists have struggled to devise a reasonably short synthetic pathway that can be used to produce morphine on an economically viable commercial scale. Building on decades of research by multiple groups, Vimal Varghese and . . .
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