Linker Helps Detect Protein Partners | August 25, 2014 Issue - Vol. 92 Issue 34 | Chemical & Engineering News
 
 
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Volume 92 Issue 34 | p. 4 | News of The Week
Issue Date: August 25, 2014 | Web Date: August 22, 2014

Linker Helps Detect Protein Partners

Biochemistry: Cleavable photo-cross-linker aids protein-protein interaction analysis
Department: Business
Keywords: petrochemical, Taiwan, explosion, pipeline, propylene, accident

Protein-protein interactions play important roles in normal body processes and in disease. Scientists often lock interacting proteins together with cross-linkers to better understand these interactions—information that can help lead to drugs that block or promote the protein-protein interplay. Now, a research team in China has developed a cleavable photo-cross-linking agent that can be genetically engineered into proteins to help study the interactions in living cells.

Cross-linking ensures that protein partners stay together for analysis, especially . . .

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