Volume 92 Issue 42 | p. 30 | Concentrates
Issue Date: October 20, 2014

Fluorinated Coating Repels Blood On Medical Devices

Combination of tethered and liquid perfluorocarbons wards off blood clotting without the need for anticoagulants
Department: Science & Technology
News Channels: Biological SCENE, Materials SCENE
Keywords: medical devices, coating, perfluorocarbons, anticoagulant

A challenge with implantable medical devices is preventing the formation of blood clots. One strategy to mitigate the problem has been to attach the anticoagulant heparin to device surfaces, but the sulfated glycosaminoglycan can leach away and cause unintended bleeding. As an alternative to heparin, Donald E. Ingber, founding director of the Wyss Institute at Harvard University, and coworkers have developed a tethered liquid perfluorocarbon (TLP) coating that repels blood and . . .

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