Simulations suggest that ions traverse cell-membrane pores without intervening water molecules
Cell-membrane-spanning potassium ion channel proteins regulate heartbeat and generate nerve impulses—they are essential to health. And for years, researchers have had a healthy debate about how ions move through these channels. X-ray crystallographic studies show a cylinder-shaped selectivity filter inside the channels, with four contiguous ion-binding sites. The X-ray picture and other studies suggest that potassium ions take turns with intervening water molecules on the narrow path through the channels. But a multi-institution group of . . .
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- Chemical & Engineering News
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