Issue Date: February 17, 2014
Small Molecules Block Activity Of MicroRNA Transcription Factors
Researchers have developed a computational method that identifies small molecules that block the function of microRNAs (miRNAs), which are important cellular targets for cancer and other diseases (Nat. Chem. Biol. 2014, DOI: 10.1038/nchembio.1452). One of the agents has a selective type of anticancer activity, suggesting that a drug based on it might have fewer side effects than conventional cancer chemotherapies.
miRNAs are three-dimensionally folded . . .
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