Implantable Metal-Filled Particles Activate Cancer Drug | February 24, 2014 Issue - Vol. 92 Issue 8 | Chemical & Engineering News
Volume 92 Issue 8 | p. 6 | News of The Week
Issue Date: February 24, 2014

Implantable Metal-Filled Particles Activate Cancer Drug

Oncology: Strategy restricts chemotherapeutic agent's toxicity in cells
Department: Science & Technology | Collection: Life Sciences
News Channels: Biological SCENE, Organic SCENE, Nano SCENE
Keywords: chemistry, chemotherapy, palladium, organometallics, fluorouracil, side effects

Chemotherapy drugs don’t attack just malignant cells—a long-standing problem in cancer treatment. As they flow through the bloodstream, the drugs also kill healthy cells and cause debilitating side effects such as hair loss, fatigue, and nausea.

Researchers at the University of Edinburgh, in Scotland, want to reduce these adverse reactions by modifying chemotherapeutics so that the compounds become toxic only when they reach tumors. The team, led by Asier Unciti-Broceta, proposes adding . . .

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