Issue Date: June 29, 2015 | Web Date: June 25, 2015
Key Enzyme Poppies Use To Synthesize Morphine Identified
For years, researchers have been unable to identify an enzyme that the opium poppy Papaver somniferum uses to synthesize morphine. Without the enzyme, which sits in the middle of the plant’s biosynthetic pathway and converts the intermediate (S)-reticuline into (R)-reticuline, poppies can’t make morphine or related opioid compounds, known collectively as morphinans.
Now a team led by Ian A. Graham of the University of York, in England, has finally identified that . . .
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- Chemical & Engineering News
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