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Biological Chemistry

More Hopes For Regenerating Tissue

July 6, 2015 | A version of this story appeared in Volume 93, Issue 27

I was lying in a recovery room hospital bed, passing time by reading C&EN, when I happened upon the article about 1,4-DPCA (1,4-dihydrophenonthrolin-4-one-3-carboxylic acid) and tissue regeneration (June 8, page 7). Ironically, I was post-blood patch for the treatment of a spontaneous cerebrospinal fluid (CSF) leak, which is caused by a tear in the dura.

I can’t help but wonder if 1,4-DPCA could be utilized for dural repair. As CSF leaks are quite debilitating, it would be exciting if such research were pursued.

Jocelyn McQueen
Thousand Oaks, Calif.

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