Volume 93 Issue 28 | p. 25 | Concentrates
Issue Date: July 13, 2015

How Transcription Factors Depart Their Targets In Cells

Molecular Biology: Higher cellular levels promote faster unbinding of transcription factors from genes
Department: Science & Technology
News Channels: Biological SCENE
Keywords: transcription factor, gene, transcription

Binding of transcription factor proteins to genes is known to initiate gene transcription to mRNA and subsequent translation to protein. But the influences that cause transcription factors to detach from their gene targets in living cells are not as well understood. In vitro studies have shown that higher levels of free transcription factors in solution are associated with faster transcription factor release or faster exchanges of one for another. Peng Chen and . . .

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